Newsletter | May 8, 2024

05.08.24 -- Pioneering The First Cell Therapy For Solid Tumors

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Webinar: Jumpstart Your QMSR Transition: Get Ahead of Evolving Regulations

Save the date for May 16th! During this Cell & Gene webinar, Kymanox experts in Quality and Regulatory Affairs will guide you through your transition to the QMSR, while discussing key changes and impact from new requirements, and ensuring that your company achieves compliance by the February 2026 effective date. Click here to learn more.

FROM THE EDITOR

Pioneering The First Cell Therapy For Solid Tumors

I spoke to Iovance Biotherapeutics to learn about the company's preparation leading up to the approval of Amtagvi, the first FDA-approved tumor-infiltrating lymphocyte (TIL) therapy aimed at treating solid tumors.

FEATURED EDITORIAL

Reducing Variability For Apheresis Material For Autologous Cell Therapy

Expert panelists address why apheresis material for autologous cell therapy is subject to variability related to its limited quantity, patient differences, and variations across apheresis facilities.

INDUSTRY INSIGHTS

A Robust Alternative To Plasmid DNA For AAV Production

Review a comparison of side-by-side plasmids and neDNA for AAV production in the Pro10 cell line, using different AAV capsid serotypes and productions scales.

Converting iPSC To T Cells: Key Challenges And Considerations

Explore how by addressing challenges in differentiation, clone selection, and manufacturing, iPSC-based T cell therapies could revolutionize cancer treatment and other diseases.

The Future Of Plasmid DNA Upstream Optimization

Understand why an optimized upstream manufacturing process is vital for meeting the increasing demand for plasmid DNA in various therapeutic and vaccine applications.

Why Early Market Access Planning Is Crucial In CGT Commercial Strategy

Bringing cell and gene therapies (CGTs) to market and ensuring patient access is a complex process. Discover how developing a market access strategy and partnering with experts can help.

Accelerating Treg Therapy Manufacturing

Learn about the strategies that helped accelerate the development timeline and build a process to isolate, engineer, and expand mature, thymic Tregs.

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Genome editing holds immense promise for treating genetic diseases, but off-target effects remain a significant concern. To ensure the safety and efficacy of genome editing therapies, researchers are developing various strategies to reduce off-target effects. Register today for the next Cell & Gene Live. Attendance is free thanks to the support of Bio-Techne.

SOLUTIONS

Expert Clinical Decision Making For Complex Combination Products

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