INSIGHTS ON CELL & GENE THERAPY DISCOVERY
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Potent Immune Response With Vernal’s LNP-mRNAs
As mRNA medicine continues to evolve, understand how trusted manufacturing partners will continue to play a pivotal role in translating innovative concepts into clinical reality.
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How mRNA Technology Engineers Next-Generation Antibodies
Monoclonal antibodies (mAbs) stand as pivotal drug products and biochemical reagents in the 21st century. Explore how mRNA-encoded antigens could revolutionize antibody discovery.
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Novel Plasmid DNA-Encoded Poly(A) Tails For mRNA Synthesis
Here, we evaluate the stability of these variant poly(A) regions and the biological activity of the mRNA containing the variant poly(A) tails made from these templates.
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Effects Of mRNA Capping Technologies
This study compares two important mRNA capping technologies by evaluating the mRNA integrity, percent Cap1 content, dsRNA content, in vivo expression, and innate immune activation in mice.
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Methods for mRNA Poly(A) Sizing
This study used Oxford Nanopore Technologies' Direct RNA Sequencing Kit and obtained successful sizing of poly(A) tail regions. The results are presented in a histogram and table format.
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Assessing Doggybone DNA For In Vitro Transcription
In this study, we evaluated the performance of two dbDNA IVT templates, each encoding the same mRNA (firefly luciferase or Fluc), by looking at the mRNA purity and in vivo potency of the mRNA IVT’d from each template.
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Comparing Mass Photometry And CDMS For AAV analysis
Review the results of a study comparing mass photometry and CDMS techniques for their ability to distinguish AAV loading distributions and evaluate adeno-associated virus (AAV) capsid content.
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The Critical Role Of Comparative Analytical Assessments
Utilize our expert analytical testing services to unlock the potential of biosimilars and bring cost-effective treatments to market faster.
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Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing
Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.
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Analytical Considerations For mRNA-Based Therapies
Uncover why leveraging strong scientific expertise and comprehensive testing techniques will be vital in expediting development and upholding the integrity of these life-saving treatments.